eProd Bioreactor SU
Single use double purpose Bioreactor
eProd Bioreactor SU is a stirred tank reactor with a single-use bag (eBAG 3D STR), designed for cell culture and microbial fermentation processes at 300 L and 1000 L scales. It combines a stainless steel vessel with a jacket for thermal control, mechanical agitation and an automation system geared towards operation and traceability.
Specification summary
| Parameter | Value |
|---|---|
| Available volumes | 50 / 100 / 200 / 500 L |
| Port configuration | 4 to 11 ports, customisable in number, location, and type |
| Agitation | Magnetic stirring, 4 pitch-blade impellers at the bottom, depending on configuration |
| Sterilisation | Gamma irradiation, ready-to-use product |
| Manufacturing | ISO 7 cleanroom |
| Film technology | 5-layer structure with EVOH barrier, inner ULPDE layer in contact with product |
| Working temperature | 5-40 °C |
| Storage temperature | -20 to 60 °C |
| Maximum pressure | 50 mbar |
| Leak test | Optional, upon request |
eBag 3D Mixer
Single-use 3D bag for mixing and liquid handling in bioprocesses
The eBag 3D Mixer is a single-use 3D bag designed for mixing and liquid handling in bioprocesses. It is compatible with TECNIC ePLUS Mixer SU systems from 50 to 500 L and can be configured with 4 to 11 ports depending on the required process layout. Gamma irradiation, ISO 7 cleanroom manufacturing, and magnetic stirring compatibility make it suitable for controlled media and buffer preparation workflows.
Discover the complete eBag portfolio
Mixing and liquid handling applications
Configurable ports, lines, and process layouts
Film structure, cleanroom manufacturing, and operating conditions
Testing, qualifications, and documentation
Main specifications
Below, you can explore the main specifications and key design details of the eBag, organised by topic for quick review.
Ports, lines and connections
The bag allows porting to be configured in a typical range of 4 to 11 ports. The selection of number, location, type of ports, connectors, tubing lengths, and sensors is defined according to the URS, process needs, and requested reference.
| Function / line | Description (guideline) |
|---|---|
| Inlet (filling) | Inlet line with configurable tubing and adapters. |
| Harvest / Drain | Drain port with configurable interface, for example aseptic connectors or equivalent. |
| Vent + filter | Vent line with 0.22 µm filter, with filter type and terminal defined on request. |
| Addition ports | Addition lines with tubing for peristaltic pump use and/or configurable connections, with quantity defined as required. |
| Sampling | Sampling line with kit according to SOP or customer procedure. |
| Sensor ports (optional) | Integration of single-use sensors such as pH and/or conductivity, as required. |
| Agitation | Magnetic stirring port for integration with ePLUS Mixer SU. |
Typical porting packages (for guidance)
| Package | Example configuration (functions) | Typical application |
|---|---|---|
| MIX base (4) | Inlet + Harvest/Drain + Vent (0.22 µm) + Magnetic stirring. | Basic mixing with filling and emptying. |
| MIX + Additions (9) | MIX base + addition lines (up to 4) + Sampling. | Preparation of media/buffers with additions and sampling. |
| MIX + Monitoring (11) | MIX + Additions + pH sensor (SU) + conductivity sensor (SU). | Processes with parameter control and monitoring. |
| Custom (4-11) | Selection of number, location, and type according to URS/process. | Specific cases, including sensors, extra ports, and special interfaces. |
The inner layer (ULPDE) is in contact with the product.
The EVOH layer acts as a gas barrier to help control permeability and preserve storage conditions.
Manufacturing and sterilisation
Manufactured in an ISO 7 cleanroom (controlled environment).
Sterilisation by gamma irradiation (ready-to-use).
Irradiation included: 25 kGy.
Indicated dose range: 25-50 kGy.
Operating conditions
Working temperature: 5-40 °C.
Storage temperature: -20 to 60 °C.
Maximum pressure: 50 mbar.
Note: pressure and temperature limits must be validated against the specific reference plan provided.
External dimensions (mm)
| Volume (L) | Width | Depth | Height |
|---|---|---|---|
| 50 | 370 | 370 | 400 |
| 100 | 470 | 470 | 497 |
| 200 | 590 | 590 | 632 |
| 500 | 800 | 800 | 859 |
Testing, qualifications and documentation
Tests and qualifications include, but are not limited to:
USP <788>,
USP <88> (Systemic / Intracutaneous / Implantation),
USP <87> (Cytotoxicity),
USP <85> (LAL),
USP <661.1>,
ISO 10993-4,
and EP <3.2.2.1>.
For regulated applications, request the complete package of certificates and the associated validation guide for extractables, leachables, and compatibilities, depending on the final configuration.
Typical documentation available, depending on project and configuration:
• Batch irradiation / dosimetry certificate.
• Certificates of materials / film and declaration of conformity.
• Batch traceability and expiry date (printed on bag label).
• Port layout / configuration and documentation associated with the requested reference (upon request).
• Applicable test and qualification results.
